What are you looking for? Search Common searches: Intranet, Contact, Map, Professionals, Teaching units, Research groups, Fulltext search Tipus de contingut Professionals Projects Teaching Units Collaborating entities News Activities - Any - Search Research groups Genetic medicine The group’s lines of research include studying different genetic pathologies such as foetal alcohol syndrome, cleft lip and cleft palate, or the role of genetic restructuring in congenital heart defects. They are also studying the genetic foundations of some heart diseases, congenital adrenal hyp Research groups Growth and development In this field, they are working on the clinical, biochemical and molecular aspects of pathologies related to development patterns, growth retardation, sexual development disorders or aspects related to childhood obesity, such as metabolic complications or therapeutic approaches. Research groups Growth factors They are developing innovative therapeutic strategies to treat HER2 positive tumours and to identify mechanisms of resistance to current treatments. Working on the characterisation of the role of premature senescence in the progression and treatment of breast cancer, and the study of the implicat Research groups Experimental Therapeutics Group We are working on developing PI3-K predictive pharmacodynamic biomarkers, as well as CDK4/6 inhibitors. Revealing new mechanisms of resistance against BRCA1/2 germline therapy in breast cancer, and establishing a preclinical model of patients with breast cancer, to explore the hypotheses based o Research groups Models of cancer therapies group Focused on designing and validating the therapeutic impact of Myc-tag peptides in vitro and in vivo; comparing and contrasting possible Myc inhibitors in murine cancer models (lung cancer, glioma, metastatic breast cancer, melanoma and multiple myeloma). And studying the effects of Myc inhibition Research groups Gene expression and cancer By studying intratumoural heterogeneity, we are working to better understand the molecular mechanisms involved in cancer stem cells/stem cells. Developing methods for non-invasive molecular diagnosis by studying circulating biomarkers, and creating brain tumour models derived from patients in rat Research groups Stem cells and cancer The group’s strategic working lines are describing the key molecular mechanisms responsible for the self regeneration of stem cells in colon cancer (CoCSC); identifying the main molecules responsible for metastasis development in colon cancer. As well as determining the importance of new transcri Research groups Breast cancer Among the group’s current objectives is putting into practice tumour sequencing in patients with breast cancer. We are studying the efficacy of PI3K/mTOR inhibitors and their relationship with mutational state, as well as continuing research on the factors involved in resistance to HER2 treatment Research groups Early clinical development of drugs The Early Clinical Development of Drugs group promotes the early development of medicines and translational research through assessment and treatment of patients in phase I trials. They work on preliminary trials for targeted treatments aimed at cell signalling and cancer stem cells. They are als Research groups Gynaecological neoplasia The work of the Gynaecological Neoplasia research group contributes to the early clinical development of drugs against gynaecological cancers, while also seeking to consolidate a translational research programme to advance precision medicine. Pagination Previous page ‹‹ Page 66 Next page ››