We are a leading healthcare campus encompassing all fields of health: from healthcare and research to teaching and management.
Professionalism, commitment and research by professionals on the Campus are the key elements in offering patients excellent care.
We are committed to research as a tool to provide solutions to the daily challenges we face in the field of medical healthcare.
We generate, transform and transmit knowledge in all areas of the health sciences, helping to train the professionals of the future.
We are defined by our vocation for communication. We invite you to share everything that happens at Vall d'Hebron Barcelona Hospital Campus, and our doors are always open.
A group of researchers from Vall d’Hebron Research, IDIBELL and UB has identified a molecule involved in bone metastasis associated with prostate cancer that could be useful in the design of new therapies for its treatment.
Prostate cancer is the most prevalent cancer in men around the world and, in fact, represented the fifth leading cause of cancer death in men in 2020. In about 70% of patients, prostate cancer cells travel into the bloodstream and eventually settle in the bones. This phenomenon, known as bone metastasis, gives rise to complications that seriously impair the patient's quality of life, as well as drastically reducing the chances of survival.
A group of researchers from Vall d'Hebron Research, Bellvitge Biomedical Research Institute (IDIBELL) and University of Barcelona (UB) have carried out a study to identify which molecules could favor bone metastasis in prostate cancer. As explained in their work, published in the journal Cancers, they have observed that tumor cells with a low expression of a specific molecule, the microRNA miR-135b, have a greater capacity to establish bone metastasis. In other words, one of the functions of miR-135b would be to avoid this complication in the more advanced stages of the disease. The results have been possible thanks to the study of patient samples from the Urology Department of the Vall d'Hebron University Hospital.
MicroRNAs are small molecules that regulate the expression of specific genes and, therefore, the cell's functioning. "Some microRNAs can promote tumor growth and others can restrict it. Therefore, if we get to know well how they work, they could represent very valuable tools to control and treat this disease," explain Dr. Anna Santamaria, head of the Biomedical Research in Urology group at Vall d'Hebron Research, and Dr. Ruth Rodríguez-Barrueco, IDIBELL researcher, and both coordinators of this work.
Dr. Mireia Olivan, now a researcher at IDIBELL and UB and first author of the study, adds that "analyzing miR-135b levels in prostate cancer cases could therefore be an indicator of the prognosis of this disease, as well as being useful when designing new treatments".
Select the newsletter you want to receive:
By accepting these conditions, you are agreeing to the processing of your personal data for the provision of the services requested through this portal, and, if necessary, for any procedures required by the administrations or public bodies involved in this processing, and their subsequent inclusion in the aforementioned automated file. You may exercise your rights to access, rectification, cancellation or opposition by writing to email@example.com, clearly stating the subject as "Exercising of Data Protection Rights".
Operated by: Vall d’Hebron University Hospital Foundation – Research Institute.
Purpose: Manage the user’s contact information.
Rights: To access, rectify, and delete personal information data, as well to the portability thereof and to limit and/or oppose their use.
Source: The interested party themselves.