From the labto the hospital

Peripheral Nervous System

Sistema nerviós perifèric a Vall d'Hebron Institut de Recerca

Our laboratory, in the Neuromuscular Disorders Unit of the Neurology Department, has a twenty-year history of clinical care and research into amyotrophic lateral sclerosis (ALS) and other motor neurone diseases (hereditary, spastic paraplegia, post-polio syndrome, Hirayama disease, spinal muscular atrophy), myasthenia gravis, genetically determined myopathies, and peripheral neuropathies.

Description

They work on the hypothesis that some cases of ALS may be due to missing genetic information or excess chromosomes. For that reason they are investigating the specific genes involved in ALS, and the contribution that DNA restructuring makes to the causes of the illness. The group’s main lines of research focus on getting to the bottom of the role genetic information and mutations play in familial ALS in order to find the connection between mutant proteins and their pathological pathways.

The group’s work also consists of looking into the effective biomarkers in the cerebrospinal fluid and the blood, allowing new ALS drugs and treatments to be assessed. As well as amyotrophic lateral sclerosis, the group is working on other peripheral nervous system diseases, such as myasthenia gravis, peripheral myopathies and neuropathies, with the aim of better understanding the clinical, genetic and pathological correlations of these conditions.

Visit the research group’s page

  
Related professionals
Dr. Josep
Gámez
Head of Section
Neurology
Lead Researcher
Peripheral Nervous System
Dra. Maria
Salvadó
Researcher
Peripheral Nervous System
 
Noticies y activitats relacionades
See more
Embedded thumbnail for World ALS Day at Vall d’Hebron
World ALS Day at Vall d’Hebron
World ALS Day at Vall d’Hebron
21.06.2017